Ceramide glucosyltransferase Polyclonal Antibody, Alexa Fluor 488 UGCG antibody Immunohistochemistry, Western HPA024124 The UDP-glucose ceramide glucosyltransferase (UGCG) is a key enzyme in the synthesis of glycosylated sphingolipids, since this enzyme generates the precursor for all complex glycosphingolipids (GSL), the GlcCer. ceramide phosphothanol amine Chinese translation: .. Rat Ceramide glucosyltransferase (Ugcg) ELISA Kit (RK08648) suitable for serum, plasma, cell culture supernatants and urine in Rat. Amazon.com: UDP Glucose Ceramide Glucosyltransferase (UGCG) BioAssay ELISA Kit (Rat), 153220-96Tests : Industrial & Scientific UDP Glucose Ceramide Glucosyltransferase (UGCG) Protein (Active) : Abbexa: : abx655856: : 50 g: : $725. Ceramide glucosyltransferase of the nematode Caenorhabditis elegans is involved in oocyte formation and in early embryonic cell division Kazuko H Nomura, Daisuke Murata, Yasuhiro Hayashi, Katsufumi Dejima, Souhei Mizuguchi, Eriko Kage-Nakadai, Keiko Gengyo-Ando, Shohei Mitani, Yoshio Hirabayashi, Makoto Ito . Anti-Ceramide glucosyltransferase antibody (ab124296) | Abcam Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. 100% guaranteed. MetaCyc EC 2.4.1.80 - biocyc.org RefSeq Summary (NR_027671): UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER. Increasing ceramide levels by the addition of short chain ceramides or the use of a glucosylceramide synthase inhibitor can be dissociated from activation of NF- B by TNF-. Ceramide Glucosyltransferase Abbreviation - 1 Forms to Abbreviate Structure Search. It is inhibited by miglustat and eliglustat, both drugs developed for the treatment of Gaucher disease . UDP Glucose Ceramide Glucosyltransferase (UGCG) BioAssay ELISA Kit Search Within. Lenti ORF clone of Human UDP-glucose ceramide glucosyltransferase (UGCG), mGFP tagged Short form to Abbreviate Ceramide Glucosyltransferase. Nicolas E.S. Guisot - Research Fellow - Redx Pharma | LinkedIn TRPV1_RAT: Trpv1: Transient receptor potential cation channel subfamily V member 1 ABclonal provide all the time-savings, convenience and performance of a high-end, commercial ELISA kit for the competitive price. The UGCG has been associated with several cancer-related processes such as maintaining cancer stem cell properties or multidrug . Show more Author Notes We are proud to list acronym of CGT in the largest database of abbreviations and acronyms. The ceramide glucosyltransferase according to claim 4, which is obtained from a mammal selected from the group consisting of human, monkey, dog, cat, cow, horse, rat and mice. Rat Ceramide glucosyltransferase (Ugcg) ELISA Kit (RK08648) In addition to sphingomyelin and ceramide, sugar derivatives of ceramides, hexosylceramides (HexCer) are the major circulating sphingolipids. One such enzyme is UDP-Glc:ceramide glucosyltransferase (EC 2.4.1.80; glucosylceramide synthase (GCS)), which catalyzes the formation of glucosylceramide (GlcCer) from ceramide and UDP-Glc ( 11. Original language. A Beginners Guide to the Metabolism, Functions and Pharmacological 22234 - Gene ResultUgcg UDP-glucose ceramide glucosyltransferase US Patent for Ceramide glucosyltransferase Patent (Patent # 6,054,309 Our Products Are Not Intended For Clinical Use. Regulation of UDP-glucose : ceramide glucosyltransferase-1 by ceramide ceramide UDPG glucosyltransferase glucocerebroside synthetase glucosylceramide synthase glycosylceramide synthetase Registry Number EC 2.4.1.80 Related Numbers 37237-44-8 Previous Indexing CERAMIDES (75-82) UDPG (75-80) Heading Mapped to *Glucosyltransferases Frequency 528 Source Adv Exp Med Biol 101:657;1978 . Ceramide glucosyltransferase - How is Ceramide glucosyltransferase Storage & Handling Store at -20C for one year. Ceramide glucosyltransferase (CGT), the enzyme responsible for the synthesis of lamellar granule glucosylceramides (GlcCer; the precursors of the stratum corneum ceramides), is localized to the. For Research Use Only. ceramide glucosyltransferase MeSH Supplementary Concept Data 2022 Ceramide glucosyltransferase Rabbit anti-Human, Polyclonal, Bioss Ceramide glucosyltransferase is an enzyme that in humans is encoded by the UGCG gene. Nutrients | Free Full-Text | ATP-Binding Cassette Transporter Family C Kegg T01001: 2629 We conclude that TNF- -induced NF-B activation occurs in Jurkat and HL-60 cell lines that do not demonstrate an increase in TNF--induced ceramide. ceramide glucosyltransferase: . Ceramide glucosyltransferase - The Institute of Physical and Chemical Ceramide glucosyltransferase UGCG Antibody - Bosterbio It is classified under EC 2.4.1.80. ceramide glucosyltransferase (glucosylceramide synthase or glct 1 or udp glucose:n acylsphingosine d glucosyltransferase or udp glucose ceramide glucosyltransferase or ugcg or ec 2.4.1.80) drugs in development by therapy areas and indications, stages, moa, roa, molecule type and key players report provides in depth analysis on ceramide 6. This enzyme is of particular interest for a number of reasons. [supplied by OMIM . Human Gene UGGT1 (uc002tpr.3) Frontiers | An Update on the Evolution of Glucosyltransferase (Gtf UDP Glucose Ceramide Glucosyltransferase UGCG ELISA Kit Ceramide glucosyltransferase | DrugBank Online How sphingolipids affect T cells in the resolution of inflammation ceramide phosphoethanolamine Chinese translation: .. Ceramide Glucosyltransferase - an overview | ScienceDirect Topics Glucosylceramide synthase and apoptosis - PubMed Name Group Description Reference Set Size; YWHAG: 5: 14-3-3 protein gamma: 11: SFN: 5: 14-3-3 protein sigma Glucosylceramide . Description: Homo sapiens UDP-glucose glycoprotein glucosyltransferase 1 (UGGT1), transcript variant 2, non-coding RNA. GlcCer and GalCer are synthesized by UDP-Glc (or Gal):ceramide glucosyltransferases, hence, a major determinate of the types of glycosphingolipids made by a given cell type will be whether it expresses one or both of these genes. Description Product name Recombinant Human Ceramide glucosyltransferase protein See all Ceramide glucosyltransferase proteins and peptides Expression system Wheat germ Accession Q16739 Protein length Protein fragment Animal free No Nature Recombinant Species Human Sequence Ceramide glucosyltransferase Ceramide glucosyltransferase (or glucosylceramide synthase) is a glucosyltransferase enzyme involved in the production of glucocerebroside. An isolated ceramide glucosyltransferase having the amino sequence of SEQ ID No. For price inquiries, please feel free to contact us through the form on the left side. Crucial role of glucosylceramide synthase in the regulation of stem cell-like cancer cells in B16F10 murine melanoma. We and other groups have previously elucidated that koji contains glycosylceramides, including N-2-hydroxyoctadecanoyl-1-O--d-glucosyl-9-methyl-4,8 . MedChemExpress provides thousands of inhibitors, modulators and agonists with high purity and quality, excellent customer reviews, precise and professional product citations, tech support and prompt delivery. Products Building Blocks Explorer Technical Documents Site Content Papers Genes Chromatograms. Query Target Key Target Name Description P-Value MaxTC; compound_1 . Glucosylceramide synthase (GCS), converting ceramide to glucosylceramide, catalyzes the first reaction of ceramide glycosylation in sphingolipid metabolism. Purification and Characterization of UDP-glucose:Ceramide Chinese translation for " ceramide phosphothanol amine The product, glucosylceramide, is the core structure of more than 300 GSLs. Species Reactivity: Human; Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western . The ceramide glucosyltransferase according to claim 4, which is obtained from a mammal selected from the group consisting of human, monkey, dog, cat, cow, horse, rat and mice. Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates. Avoid repeated freeze-thaw cycles. Please click for detailed translation, meaning, pronunciation and example sentences for ceramide phosphoethanolamine in Chinese We will get back to you as soon as possible. GSLs are a group of membrane components that contain lipid and sugar moieties. Ceramide Glucosyltransferase - Encyclopedia Information [5] [6] [7] Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. The ceramide glucosyltransferase (EC 2.4.1.80) activity was not detected in GM-95 cells. Expression Cloning of a cDNA for Human Ceramide Glucosyltransferase Entry - *602874 - UDP-GLUCOSE CERAMIDE GLUCOSYLTRANSFERASE; UGCG - OMIM Advanced Search. ). Anti-Ceramide glucosyltransferase antibody (ab124296) Datasheet SDS Submit a review Submit a question References (2) $420 Product size 100 g Add to basket Order now and get it on Monday September 05, 2022 Custom quote | Bulk request Shipping info $50.00 to United States Same day delivery on Boston area orders placed by 1.00 PM This item requires custom production and lead time is between 5-9 weeks. See also [ edit] Glucocerebroside For Research Use Only. Welcome! It is inhibited by miglustat and eliglustat, both drugs developed for the treatment of Gaucher disease. The enzyme catalyzes the first glycosylation step of glycosphin Ceramide glucosyltransferase Antibody (BS-0701R) - Thermo Fisher Scientific Find ceramide glucosyltransferase (glucosylceramide synthase) and related products for scientific research at MilliporeSigma. The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for all glycosphingolipids (GSL), which are essential for proper cell function. ceramide glucosyltransferase < Glycosyltransferases (Glycoside Eduardo Salustiano - Research Associate - LinkedIn Stressed cells increase de novo biosynthesis of ceramides, which return to sub-toxic levels after UGCG mediates incorporation into GlcCer. Ceramide Glycosyltransferase is the first step in the Glycosphingolipid synthesis; first glycosylation step. May also serve as a "flippase". For short term storage and frequent use, store at 4C for up to one month. Ceramide glucosyltransferase activity Specific Function Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. 6. We have demonstrated that it is possible to selectively either strongly inhibit ER--glucosidases and ceramide glucosyltransferase or restore the A series of neoglycoconjugates derived from deoxynojirimycin has been prepared by click connection with functionalised adamantanes. CGT: Ceramide Glucosyltransferase - Abbreviation Finder Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates. Ceramide Glucosyltransferase - an overview | ScienceDirect Topics UDP-glucose ceramide glucosyltransferase activates AKT, promoted In IBD patients and in a DSS induced colitis mouse model UGCG activity was decreased, and knockdown of UGCG resulted in Treg decrease and CD4 effector cell increase (Table1). This antibody reacts with Human, Mouse, Rat. There was no significant difference of sialyllactosylceramide synthase activity, however, between GM-95 and . Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal disorder caused by the deficiency of arylsulfatase A (ASA), resulting in impaired degradation of sulfatide, an essential sphin. We have isolated a cDNA encoding human ceramide glucosyltransferase (glucosylceramide synthase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, EC 2.4.1.80) by expression cloning using as a recipient GM-95 cells lacking the enzyme. An isolated ceramide glucosyltransferase having the amino sequence of SEQ ID No. Cite This Product Ceramide glucosyltransferase - Wikipedia This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. UDP-glucose: Ceramide glucosyltransferase (UGCG) SEA Web Server. ELISA test kits can be sandwich ELISA. UGCG UDP-glucose ceramide glucosyltransferase [ (human)] The enzyme catalyzes the transfer of glucose to ceramide, the first committed step in glycolipid biosynthesis. Ceramide glucosyltransferase (or glucosylceramide synthase) is a glucosyltransferase enzyme involved in the production of glucocerebroside. UniProt The UDP-glucose ceramide glucosyltransferase (UGCG) is the first enzyme in the process of glycosphingolipid biosynthesis. Pfam Domain Function Glyco_transf_21 ( PF13506) Transmembrane Regions 11-32 196-215 288-304 310-328 349-369 Cellular Location Golgi apparatus membrane Glucosylceramide synthase (GCS) is an enzyme inherent to ceramide metabolism. This glycosylation by GCS is a critical step regulating the modulation of cellular activities by controlling ceramide and glycosphingolipids (GSLs). Full article: Developing therapeutic approaches for metachromatic SEA Search Server The following image shows one of the definitions of CGT in English: Ceramide Glucosyltransferase. UDP Glucose Ceramide Glucosyltransferase (UGCG) ELISA Kit Technique ELISA kit, ELISA, ELISAs Enzyme-linked immunosorbent assay 90320007 SNOMED code are used by the medical researcher for detection of human, mouse, proteins are supplied in coated 96 well plates to be stored at +4C. ceramide glucosyltransferase related products. The precise mechanisms underlying . UDP-glucose ceramide glucosyltransferase activates AKT . Protein target information for Ceramide glucosyltransferase (human). We have shown that silencing of ABCA1 transmembrane protein function for instance in cases of loss of function of ABCA1 gene results in low levels of HDL as well as a concomitant reduction in plasma HexCer levels. Applications Products Services Support. The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to We can custom produce according to your specifications. It is therefore of great interest to investigate how Gtf genes have evolved in Streptococcus. Ceramide glucosyltransferase - Wikipedia Hero Dictionary SEA Search Server The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. Chinese translation for " ceramide phosphoethanolamine The UDP-glucose ceramide glucosyltransferase (UGCG) is a key enzyme in the synthesis of glycosylated sphingolipids, since this enzyme generates the precursor for all complex glycosphingolipids (GSL), the GlcCer. It is inhibited by miglustat and eliglustat, both drugs developed for the treatment of Gaucher disease. Ceramide Glucosyltransferase (Glucosylceramide Synthase or GLCT 1 or CGT = Ceramide Glucosyltransferase Looking for general definition of CGT? Tested in WB applications. Ceramide glucosyltransferase (or glucosylceramide synthase) is a glucosyltransferase enzyme involved in the production of glucocerebroside. The UDP-glucose ceramide glucosyltransferase (UGCG) is a key enzyme in the synthesis of glycosylated sphingolipids, since this enzyme generates the precursor for all complex glycosphingolipids (GSL), the GlcCer. The UGCG has been associated with several cancer-related processes such as maintaining cancer stem cell properties or multidrug resistance induction. Fermentation | Free Full-Text | Glycosylceramides Purified from the Wegner, M.-S., Schmel, N., Gruber, L., rtel, S. B., Kjellberg, M. A., Mattjus, P., Grsch, S. (2018). However, proteins involved in hepatic . [provided by RefSeq, Dec 2014] 2.4.1.80 ceramide glucosyltransferase 7357 (UGCG) Glycosyltransferases [BR:hsa01003] Glycolipid biosynthesis Glycosphingolipid 7357 (UGCG) BRITE hierarchy: SSDB: Ortholog Paralog Gene cluster GFIT: Motif: Pfam: Glyco_transf_21 Glyco_tranf_2_3 Glyco_trans_2_3 Glycos_transf_2 Chitin_synth_2: Motif: Other DBs: NCBI-GeneID: 7357: NCBI-ProteinID: NP . Ceramide glucosyltransferase - MyScienceWork US Patent for Ceramide glucosyltransferase Patent (Patent # 5,780,284 A Beginners Guide to the Metabolism, Functions and Pharmacological Potential of Sphingolipids Nicholas JD Wright 1 * 1 Wingate University School Of Pharmacy, Wingate University, Wingate, North Carolina 28174, United States * Corresponding Author(s): Nicholas JD Wright Wingate University School Of Pharmacy, Wingate University, Wingate, North Carolina 28174, United States 1 popular form of Abbreviation for Ceramide Glucosyltransferase updated in 2021 Ceramide glucosyltransferase (human) | Protein Target - PubChem US5780284A - Ceramide glucosyltransferase - Google Patents It is classified under EC 2.4.1.80. [1] It is classified under EC 2.4.1.80 . Not for use in diagnostic procedures. Not for use in diagnostic procedures. (2011) Ceramide glucosyltransferase of the nematode Caenorhabditis elegans is involved in oocyte formation and in early embryonic cell division. Koji, which is used for manufacturing Japanese traditional fermented foods, has long been safely used as a cosmetic product. Udp(Ugcg)() - - __- Ceramide glucosyltransferase of the nematode - Oxford Academic Dissociation of endogenous cellular ceramide from NF-B activation GlcCer is the core component of glycosphingolipids/GSLs, amphipathic molecules consisting of a ceramide lipid moiety embedded in the outer leaflet of the membrane, linked to one of hundreds of different externally oriented oligosaccharide structures ( PubMed: 8643456 ). elisa ceramide glucosyltransferase(EC 2.4.1.80) - Creative Enzymes Find diseases associated with this biological target and compounds tested against it in bioassay experiments. 4p02 chain A; CAZy and TCDB also includes other proteins: Bacterial cellulose synthase di-GMP-binding regulatory subunit; Identifiers Ceramide glucosyltransferase Antibody, BS-0701R, from Bioss. PE-Cy3 ZY613915LAB Boster Bio Anti-Ceramide glucosyltransferase UGCG Antibody catalog # A10209. Lamellar Granule Biogenesis: A Role for Ceramide Glucosyltransferase Martin Wegner - Head of R&D and Customer Solutions - Vivlion GmbH UGCG - Wikipedia Need abbreviation of Ceramide Glucosyltransferase? The CGT means Ceramide Glucosyltransferase. US5780284A US08/663,713 US66371396A US5780284A US 5780284 A US5780284 A US 5780284A US 66371396 A US66371396 A US 66371396A US 5780284 A US5780284 A US 5780284A Authority US Unite US EN. ceramide glucosyltransferase (glucosylceramide synthase) Glucosylceramide in T cells regulates the pathology of inflammatory bowel disease. Anti-UGCG antibody produced in rabbit (Anti-Ceramide glucosyltransferase ); Prestige Antibodies Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution; Suitable for immunohistochemistry; Prestige Antibodies are highly characterized and extensively validated anti ceramide glucosyltransferase Medicine & Life Sciences 100%. Please click for detailed translation, meaning, pronunciation and example sentences for ceramide phosphothanol amine in Chinese . Sci-Hub | UDP-glucose ceramide glucosyltransferase activates AKT Wikizero - Cellulose synthase (UDP-forming) The subject invention provides a novel ceramide glucosyltransferase having catalytic activity of glucose transfer from UDP-Glc to ceramide, and a nucleic acid sequence encoding the ceramide glucosyltransferase. ceramide glucosyltransferase | MedChemExpress Life Science Reagents They are present in essentially all animal cells and are believed to have important roles in various cellular processes. Ceramide glucosyltransferase Jan 28, 1998 - The Institute of Physical and Chemical Research The subject invention provides a novel ceramide glucosyltransferase having catalytic activity of glucose transfer from UDP-Glc to ceramide, and a nucleic acid sequence encoding the ceramide glucosyltransferase.
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